Efficacy of Prostate-Specific Antigen to Categorize Men with Prostate Pathology into Benign, Premalignant, and Malignant Lesions
نویسندگان
چکیده
منابع مشابه
Age Specific Reference Levels of Serum Prostate-Specific Antigen, Prostate Volume and Prostate Specific Antigen Density in Healthy Iranian Men
Background: It is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum PSA in Iranian population. Objective: To determine age-specific reference ranges for serum prostate-specific antigen (PSA) concentration and PSA density (PSAD) and prostate volumes in a population of he...
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There are emerging data on novel tumor markers such as matrix metalloproteinase-2 (MMP-2 or gelatinase-A), which play a key role in tissue invasion and metastasis. We designed an investigation to assess the usefulness of MMP-2 activity as compared to prostate specific antigen (PSA) in cancer staging process. We have analyzed the circulating form of MMP-2 in serum samples of patients suffering f...
متن کاملPremalignant and malignant prostate lesions: pathologic review.
BACKGROUND High-grade prostatic intraepithelial neoplasia (HGPIN) is currently the only recognized premalignant lesion of prostatic carcinoma. METHODS This review article discusses HGPIN, its link to prostatic adenocarcinoma, and the significance of its presence on needle biopsy. The criteria and clinical impact of the diagnosis of atypical small acinar proliferation on needle biopsy are revi...
متن کاملInvestigation of the relationship between prostate specific antigen doubling time and the severity of a malignant tumor of the prostate
Background: Prostate cancer has been reported as a worldwide important kind of cancer and the second most common cause of cancer-related mortality among men. Prostate-specific antigen (PSA) serum level is one of the most important markers of prostate cancer diagnosis. While PSA level helps predict the risk of prostate cancer development, researchers still looking for ways to increase the accura...
متن کاملage specific reference levels of serum prostate-specific antigen, prostate volume and prostate specific antigen density in healthy iranian men
background: it is relevant to highlight that there is not a precise and perfect report on either 95 percentile value (upper limit of normal range) or on appropriate reference intervals for serum psa in iranian population. objective: to determine age-specific reference ranges for serum prostate-specific antigen (psa) concentration and psa density (psad) and prostate volumes in a population of he...
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ژورنال
عنوان ژورنال: Journal of Medical Sciences and Health
سال: 2016
ISSN: 2394-9481,2394-949X
DOI: 10.46347/jmsh.2016.v02i02.001